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Ôçµã³ÐÈÏÒßÃç×èÖ¹²»ÁË, ÄÇôºóÐø¸ÃÔõô×ö¾ÍºÜÇå³þ¡£¾ÍżÙ×°ÓÐÓ㬺óÃæµÄ¼Æ»®¾ÍºÜÂé·³¡£
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(ÒýÓà hongren:Ôçµã³ÐÈÏÒßÃç×èÖ¹²»ÁË, ÄÇôºóÐø¸ÃÔõô×ö¾ÍºÜÇå³þ¡£¾ÍżÙ×°ÓÐÓ㬺óÃæµÄ¼Æ»®¾ÍºÜÂé·³¡£ ¼ÌÐø×°ÏÂÈ¥£¬¾ÍÊÇÒ»ÕëÒ»Õë´òÏÂÈ¥£¬Ò»»á¶ù¿ªÒ»»á¶...)Quote"The world may be taken by surprise but that doesn't include us. It remains to be seen whether Omicron can outcompete Delta (to be confirmed). If that¡¯s the case, we're definitely not in good shape.

In case of CoV, innate immunity protects the individual and the 'herd' ( sterilizing immunity, no natural selection pressure, herd immunity) whereas adaptive immunity induced with leaky vaccines has exactly the opposite effect.

THE big Q is whether such an immune escape variant could even resist naturally acquired Abs in people who recovered from C19 disease. I am, indeed, cautious and worried about ADE, even in the unvaccinated who recovered from C-19 disease as they may no longer be able to control viral infection. ADE would equal ¡®enhanced virulence¡¯. Difficult to predict.

Mass vaccination has compressed the evolutionary trajectory of the virus from a few hundred years (?) down to one year. Hope that naturally primed individuals can deal with that speed."

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