科兴 国药针对 both N 蛋白和 S 蛋白??
灭活疫苗
一般被称为全病毒疫苗,不会提取部分特征。
关于delta的变体信息:
Mutations in B.1.617.2 variant
The spike protein of B.1.617.2 variant contains nine mutations in the S1 subunit and one mutation in the S2 subunit. In the S1 subunit, five mutations are present in the N-terminal domain containing binding sites (epitopes) for neutralizing antibodies. In addition, two mutations are present in the receptor-binding domain of the S1 subunit, which is known to influence antibody-mediated neutralization and infectivity. Among the three remaining mutations, two are known to increase angiotensin-converting enzyme 2 (ACE2) binding, viral replication, and spike protein cleavage at the S1/S2 site
感觉还是老老实实混打吧,灭活疫苗已经在开始基于delta重新开发新疫苗了,不知道mrna有没有开始重提提取特征
关于delta的变体信息:
Mutations in B.1.617.2 variant
The spike protein of B.1.617.2 variant contains nine mutations in the S1 subunit and one mutation in the S2 subunit. In the S1 subunit, five mutations are present in the N-terminal domain containing binding sites (epitopes) for neutralizing antibodies. In addition, two mutations are present in the receptor-binding domain of the S1 subunit, which is known to influence antibody-mediated neutralization and infectivity. Among the three remaining mutations, two are known to increase angiotensin-converting enzyme 2 (ACE2) binding, viral replication, and spike protein cleavage at the S1/S2 site
感觉还是老老实实混打吧,灭活疫苗已经在开始基于delta重新开发新疫苗了,不知道mrna有没有开始重提提取特征
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