The profile of the boss. Can get from google ALL | ABC | DEF | GHI | JKL | MNO | PQRS | TUV | WXYZ Yijun RUAN, Ph.D. Senior Group Leader Assoc Director, Genomic Technologies ruanyj@gis.a-star.edu.sg RESEARCH FOCUS My primary interest is to elucidate the structures and dynamics of all functional DNA elements in complex genomes through transcriptome characterizations and genome interrogation. To facilitate such understanding we have developed paired-end-ditag (PET) based high throughput and high precision DNA sequencing and mapping methodologies. We are applying these sequencing-based measurements to address complex biological questions such as how cancer cells progress and how stem cells maintain their unique properties. Another major interest of mine is to discover previously uncharacterized microbial genes and genomes that are relevant to human health. To this end, we have established a metagenome analysis capability that includes a filtration system for isolating uncultu (more...)